A scalable, efficient, and safe method to prepare high quality DNA from mycobacteria and other challenging cells

The rapid development in sequencing technology is creating an increase in demand for largely intact DNA as starting material as very long strands of DNA are sequenced directly to generate reads that are thousands of bases long. Organisms with thick cell walls are difficult to lyse, often impacting b...

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Bibliographic Details
Main Authors: L. Elaine Epperson, Michael Strong
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405579420300085