Phosphorylation of Akt at Thr308 regulates p‐eNOS Ser1177 during physiological conditions

Endothelial nitric oxide synthase (eNOS)‐derived nitric oxide (NO) plays a crucial role in maintaining vascular homeostasis. As a hallmark of eNOS activation, phosphorylation of eNOS at Ser1177 induced by activated protein kinase B (PKB/Akt) is pivotal for NO production. The complete activation of A...

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Bibliographic Details
Main Authors: Xiao‐xue Liang, Rui‐yu Wang, Yong‐zheng Guo, Zhe Cheng, Ding‐yi Lv, Ming‐hao Luo, An He, Su‐xin Luo, Yong Xia
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13194