Hesperidin inhibits the epithelial to mesenchymal transition induced by transforming growth factor-β1 in A549 cells through Smad signaling in the cytoplasm

Hesperidin, a natural compound, suppresses the epithelial-to-mesenchymal transition through the TGF-β1/Smad signaling pathway. However, studies on the detailed effects and mechanisms of hesperidin are rare. The present study showed that, for A549 alveolar epithelial cells, the anti-proliferative eff...

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Bibliographic Details
Main Authors: Zhouxin Ren, Junling Shen, Xiaofeng Mei, Haoran Dong, Jiansheng Li, Haibin Yu
Format: Article
Language:English
Published: Universidade de São Paulo 2019-10-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100566&tlng=en