Anti-Fibrotic Activity of an Antimicrobial Peptide in a Drosophila Model

Anti-Fibrotic Activity of an Antimicrobial Peptide in a Drosophila Model

Fibrotic lesions accompany several pathological conditions, including tumors. We show that expression of a dominant-active form of the Ras oncogene in Drosophila salivary glands (SGs) leads to redistribution of components of the basement membrane (BM) and fibrotic lesions. Similar to several types o...

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Bibliographic Details
Main Authors: Dilan Khalili, Christina Kalcher, Stefan Baumgartner, Ulrich Theopold
Format: Article
Language:English
Published: Karger Publishers 2021-05-01
Series:Journal of Innate Immunity
Subjects:
fibrosis
antimicrobial peptides
insect immunity
innate immunity
extracellular matrix
Online Access:https://www.karger.com/Article/FullText/516104

Internet

https://www.karger.com/Article/FullText/516104

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