High-resolution view of compound promiscuity [v2; ref status: indexed, http://f1000r.es/1ig]
Compound promiscuity is defined as the ability of a small molecule to specifically interact with multiple biological targets. So-defined promiscuity is relevant for drug discovery because it provides the molecular basis of polypharmacology, which is increasingly implicated in the therapeutic efficac...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2013-07-01
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| Series: | F1000Research |
| Subjects: | |
| Online Access: | http://f1000research.com/articles/2-144/v2 |