Monocrotaline-Induced Pulmonary Arterial Hypertension and Bosentan Treatment in Rats: Focus on Plasma and Erythrocyte Parameters

Monocrotaline-Induced Pulmonary Arterial Hypertension and Bosentan Treatment in Rats: Focus on Plasma and Erythrocyte Parameters

The objective of our study was to contribute to the characterization of monocrotaline-induced pulmonary arterial hypertension (PAH) in a rat model, with emphasis on the renin–angiotensin–aldosterone system, parameters of oxidative stress, the activity of matrix metalloproteinases, and erythrocyte pa...

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Bibliographic Details
Main Authors: Tomas Jasenovec, Dominika Radosinska, Marta Kollarova, Norbert Vrbjar, Peter Balis, Simona Trubacova, Ludovit Paulis, Lubomira Tothova, Ivana Shawkatova, Jana Radosinska
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceuticals
Subjects:
pulmonary arterial hypertension
monocrotaline
bosentan
angiotensins
oxidative stress
erythrocytes
Online Access:https://www.mdpi.com/1424-8247/15/10/1227

Internet

https://www.mdpi.com/1424-8247/15/10/1227

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