Enhanced transient expression of an anti-CD52 monoclonal antibody in CHO cells through utilization of miRNA sponge technology

Enhanced transient expression of an anti-CD52 monoclonal antibody in CHO cells through utilization of miRNA sponge technology

Chinese hamster ovary (CHO) cells are the dominant mammalian host system for the production of recombinant therapeutic proteins. Improving the viable cell density during culture of recombinant CHO cells can greatly affect the production yield. MicroRNAs (miRs) -15a and 16-1 are known as negative reg...

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Bibliographic Details
Main Authors: Morvarid Sadat Pairawan, Azam Bolhassani, Azam Rahimpour
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Research in Pharmaceutical Sciences
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2019;volume=14;issue=4;spage=335;epage=342;aulast=Pairawan

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2019;volume=14;issue=4;spage=335;epage=342;aulast=Pairawan

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