Innovative Self‐Assembly of 15‐Mer Chimeric α‐Peptide–Oligourea Foldamers toward Cl−‐Selective Ion Channels

Innovative Self‐Assembly of 15‐Mer Chimeric α‐Peptide–Oligourea Foldamers toward Cl−‐Selective Ion Channels

Constructing artificial ion channels is a challenging task. Herein, the de novo design of transmembrane ion channels made up of amphiphilic peptide–oligourea chimeric helices is described. They consist of an oligourea segment (7‐mer) attached to the C‐terminus of a short peptide (8‐mer). Mass spectr...

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Bibliographic Details
Main Authors: Chiranjit Dutta, Pannaga Krishnamurthy, Dandan Su, Jianwei Li, Sung Hyun Yoo, Gavin W. Collie, Morgane Pasco, Jingsong Fan, Min Luo, Mihail Barboiu, Gilles Guichard, R. Manjunatha Kini, Prakash Kumar
Format: Article
Language:English
Published: Wiley-VCH 2024-08-01
Series:Small Science
Subjects:
foldamers
helices
ion channels
lipid membranes
self‐assembly
structure
Online Access:https://doi.org/10.1002/smsc.202300352

Internet

https://doi.org/10.1002/smsc.202300352

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