Deciphering STAT3 signaling potential in hepatocellular carcinoma: tumorigenesis, treatment resistance, and pharmacological significance

Deciphering STAT3 signaling potential in hepatocellular carcinoma: tumorigenesis, treatment resistance, and pharmacological significance

Abstract Hepatocellular carcinoma (HCC) is considered one of the greatest challenges to human life and is the most common form of liver cancer. Treatment of HCC depends on chemotherapy, radiotherapy, surgery, and immunotherapy, all of which have their own drawbacks, and patients may develop resistan...

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Main Authors: Mehrdad Hashemi, Eisa Sabouni, Parham Rahmanian, Maliheh Entezari, Mahsa Mojtabavi, Behnaz Raei, Mohammad Arad Zandieh, Mitra Behroozaghdam, Sepideh Mirzaei, Kiavash Hushmandi, Noushin Nabavi, Shokooh Salimimoghadam, Jun Ren, Mohsen Rashidi, Rasoul Raesi, Afshin Taheriazam, Athanasios Alexiou, Marios Papadakis, Shing Cheng Tan
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Cellular & Molecular Biology Letters
Subjects:
Hepatocellular carcinoma
Liver cancer
Noncoding transcripts
STAT3
Molecular signaling
Online Access:https://doi.org/10.1186/s11658-023-00438-9

Internet

https://doi.org/10.1186/s11658-023-00438-9

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