EZH2 regulates oncomiR-200c and EMT markers in esophageal squamous cell carcinomas

Abstract EZH2, as a histone methyltransferase, has been associated with cancer development and metastasis possibly through the regulation of microRNAs and cellular pathways such as EMT. In this study, the effect of EZH2 expression on miR-200c and important genes of the EMT pathway was investigated i...

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Bibliographic Details
Main Authors: Fatemeh Nourmohammadi, Mohammad Mahdi Forghanifard, Mohammad Reza Abbaszadegan, Vajiheh Zarrinpour
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23253-2