Uncovering mechanisms of Baojin Chenfei formula treatment for silicosis by inhibiting inflammation and fibrosis based on serum pharmacochemistry and network analysis

Uncovering mechanisms of Baojin Chenfei formula treatment for silicosis by inhibiting inflammation and fibrosis based on serum pharmacochemistry and network analysis

Background: Baojin Chenfei formula (BCF), a Chinese herbal formula, has significant effects on improving the clinical symptoms of patients with silicosis. However, its active compounds and the underlying mechanisms have not yet fully been elucidated. Purpose: This study aimed to explore the underlyi...

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Bibliographic Details
Main Authors: Kangchen Li, Xinguang Liu, Runsu Hou, Hulei Zhao, Peng Zhao, Yange Tian, Jiansheng Li
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Silicosis
Baojin Chenfei formula
Serum pharmacochemistry
Network pharmacology
MAPK pathway
EGFR-PI3K-AKT pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323005869

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http://www.sciencedirect.com/science/article/pii/S0147651323005869

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