Tryptophan metabolite norharman secreted by cultivated Lactobacillus attenuates acute pancreatitis as an antagonist of histone deacetylases

Tryptophan metabolite norharman secreted by cultivated Lactobacillus attenuates acute pancreatitis as an antagonist of histone deacetylases

Abstract Background Patients with acute pancreatitis (AP) exhibit specific phenotypes of gut microbiota associated with severity. Gut microbiota and host interact primarily through metabolites; regrettably, little is known about their roles in AP biological networks. This study examines how enteroba...

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Bibliographic Details
Main Authors: Qi Zhou, Xufeng Tao, Fangyue Guo, Yu Wu, Dawei Deng, Linlin Lv, Deshi Dong, Dong Shang, Hong Xiang
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Medicine
Subjects:
Acute pancreatitis
Lactobacillus
Tryptophan
Norharman
Raftlin 1
Online Access:https://doi.org/10.1186/s12916-023-02997-2

Internet

https://doi.org/10.1186/s12916-023-02997-2

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