A rare case of Acute Lymphocytic Leukemia (ALL) presenting with double Philadelphia chromosome: relapse or secondary leukemia?

The Philadelphia chromosome is observed in 5% of pediatric acute lymphocytic leukemia (ALL) and in 25% to 50% of adult ALL cases, and is associated with poor prognosis. Double Ph in a hyperdiploid karyotype is common in chronic myeloid leukemia (CML), but rarely found in ALL. We report here the case...

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Bibliographic Details
Main Authors: Mireille Guimarães Vaz de Campos, Maria de Lourdes L. Ferrari Chauffaille, Celso Arrais Rodrigues, Everson A. Krum, Mihoko Yamamoto
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2003-01-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000300006