Pathogenic CD8 T cells in Multiple Sclerosis and its experimental models

Pathogenic CD8 T cells in Multiple Sclerosis and its experimental models

A growing body of evidence suggests that autoreactive CD8 T cells contribute to the disease process in Multiple Sclerosis (MS). Lymphocytes in MS plaques are biased toward the CD8 lineage, and MS patients harbor CD8 T cells specific for multiple central nervous system (CNS) antigens. Currently, the...

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Bibliographic Details
Main Authors: Eric S. Huseby, Priya G. Huseby, Shivanee eShah, Rebecca eSmith, Brian D. Stadinski
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Immunology
Subjects:
Autoimmunity
Central Nervous System
Multiple Sclerosis
T cells
tolerance
tcr
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00064/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00064/full

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