A phenylalanine at the extracellular side of Kir1.1 facilitates potassium permeation

ABSTRACTThe Kir1.1 (ROMK) family of weak inward rectifiers controls K secretion in the renal CCT and K recycling in the renal TALH. A single point mutant of the inward rectifier, F127V-Kir1.1b was used to investigate the K transition between the selectivity filter and the outer mouth of the channel....

Full description

Bibliographic Details
Main Authors: Henry Sackin, Mikheil Nanazashvili
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Channels
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19336950.2023.2294661