Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer

Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer

Summary: Local cryoablation can engender systemic immune activation/anticancer responses in tumors otherwise resistant to immune checkpoint blockade (ICB). We evaluated the safety/tolerability of preoperative cryoablation plus ipilimumab and nivolumab in 5 early-stage/resectable breast cancers. The...

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Bibliographic Details
Main Authors: Elizabeth Comen, Sadna Budhu, Yuval Elhanati, David Page, Teresa Rasalan-Ho, Erika Ritter, Phillip Wong, George Plitas, Sujata Patil, Edi Brogi, Maxine Jochelson, Yolanda Bryce, Stephen B. Solomon, Larry Norton, Taha Merghoub, Heather L. McArthur
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Health sciences
Oncology
Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224001019

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224001019

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