Experimental evolution reveals a general role for the methyltransferase Hmt1 in noise buffering.

Cell-to-cell heterogeneity within an isogenic population has been observed in prokaryotic and eukaryotic cells. Such heterogeneity often manifests at the level of individual protein abundance and may have evolutionary benefits, especially for organisms in fluctuating environments. Although general f...

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Bibliographic Details
Main Authors: Shu-Ting You, Yu-Ting Jhou, Cheng-Fu Kao, Jun-Yi Leu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000433