Alterations in DNA 5-hydroxymethylation patterns in the hippocampus of an experimental model of chronic epilepsy

Alterations in DNA 5-hydroxymethylation patterns in the hippocampus of an experimental model of chronic epilepsy

Temporal lobe epilepsy (TLE) is a type of focal epilepsy characterized by spontaneous recurrent seizures originating from the hippocampus. The epigenetic reprogramming hypothesis of epileptogenesis suggests that the development of TLE is associated with alterations in gene transcription changes resu...

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Bibliographic Details
Main Authors: Rudhab Bahabry, Rebecca M. Hauser, Richard G. Sánchez, Silvienne Sint Jago, Lara Ianov, Remy J. Stuckey, R. Ryley Parrish, Lawrence Ver Hoef, Farah D. Lubin
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Neurobiology of Disease
Subjects:
Epilepsy
DNA methylation
TET
Hydroxymethylation
hMeDIP
Epigenetics
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996124002389

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http://www.sciencedirect.com/science/article/pii/S0969996124002389

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