Pathway correlation profile of gene-gene co-expression for identifying pathway perturbation.

Identifying perturbed or dysregulated pathways is critical to understanding the biological processes that change within an experiment. Previous methods identified important pathways that are significantly enriched among differentially expressed genes; however, these methods cannot account for small,...

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Bibliographic Details
Main Authors: Allison N Tegge, Charles W Caldwell, Dong Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527387?pdf=render