Effects of Polyphenols on P-Glycoprotein (ABCB1) Activity

Effects of Polyphenols on P-Glycoprotein (ABCB1) Activity

P-glycoprotein (Pgp, ABCB1) is a member of one of the largest families of active transporter proteins called ABC transporters. Thanks to its expression in tissues with barrier functions and its broad substrate spectrum, it is an important determinant of the absorption, metabolism and excretion of ma...

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Bibliographic Details
Main Authors: Kuljeet Singh, Szabolcs Tarapcsák, Zsuzsanna Gyöngy, Zsuzsanna Ritter, Gyula Batta, Rosevalentine Bosire, Judit Remenyik, Katalin Goda
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
P-glycoprotein (ABCB1)
polyphenols
ATPase activity
transport activity
UIC2 reactivity
membrane fluidity
Online Access:https://www.mdpi.com/1999-4923/13/12/2062

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https://www.mdpi.com/1999-4923/13/12/2062

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