Simple virus-free mouse models of COVID-19 pathologies and oral therapeutic intervention

Simple virus-free mouse models of COVID-19 pathologies and oral therapeutic intervention

Summary: The paucity of preclinical models that recapitulate COVID-19 pathology without requiring SARS-COV-2 adaptation and humanized/transgenic mice limits research into new therapeutics against the frequently emerging variants-of-concern. We developed virus-free models by C57BL/6 mice receiving or...

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Bibliographic Details
Main Authors: Huabin Zhu, Anuj K. Sharma, Karina Aguilar, Faizan Boghani, Semih Sarcan, Michelle George, Janavi Ramesh, Joshua Van Der Eerden, Chandramukhi S. Panda, Aileen Lopez, Wenbo Zhi, Roni Bollag, Nikhil Patel, Kandace Klein, Joe White, Muthusamy Thangaraju, Bal L. Lokeshwar, Nagendra Singh, Vinata B. Lokeshwar
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Pathology
Biological sciences
Virology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224004127

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http://www.sciencedirect.com/science/article/pii/S2589004224004127

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