Megakaryocytes as the Regulator of the Hematopoietic Vascular Niche

Megakaryocytes as the Regulator of the Hematopoietic Vascular Niche

Megakaryocytes (MKs) are important components of the hematopoietic niche. Compared to the non-hematopoietic niche cells, MKs serving as part of the hematopoietic niche provides a mechanism for feedback regulation of hematopoietic stem cells (HSCs), in which HSC progeny (MKs) can modulate HSC adaptat...

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Bibliographic Details
Main Authors: Huichun Zhan, Kenneth Kaushansky
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
megakaryocyte (MK)
vascular niche
hematopoietic stem cell (HSC)
myeloproliferative neoplasms
hematopoietic microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.912060/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.912060/full

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