Regeneration linked miRNA modify tumor phenotype and can enforce multi-lineage growth arrest in vivo

Regeneration linked miRNA modify tumor phenotype and can enforce multi-lineage growth arrest in vivo

Abstract Regulated cell proliferation is an effector mechanism of regeneration, whilst dysregulated cell proliferation is a feature of cancer. We have previously identified microRNA (miRNA) that regulate successful and failed human liver regeneration. We hypothesized that these regulators may direct...

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Bibliographic Details
Main Authors: Siamak Salehi, Oliver D. Tavabie, Augusto Villanueva, Julie Watson, David Darling, Alberto Quaglia, Farzin Farzaneh, Varuna R. Aluvihare
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90009-9

Internet

https://doi.org/10.1038/s41598-021-90009-9

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