Functional dichotomy between NKG2D and CD28-mediated co-stimulation in human CD8+ T cells.

Both CD28 and NKG2D can function as co-stimulatory receptors in human CD8+ T cells. However, their independent functional contributions in distinct CD8+ T cell subsets are not well understood. In this study, CD8+ T cells in human peripheral blood- and lung-derived lymphocytes were analyzed for CD28...

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Bibliographic Details
Main Authors: Kamalakannan Rajasekaran, Va Xiong, Lee Fong, Jack Gorski, Subramaniam Malarkannan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2936560?pdf=render