WT1: A single gene associated with multiple and severe phenotypes
The Wilms tumor suppressor gene (WT1) is a transcription factor with a wide array of functions, that affects the differentiation and survival of several cell types in different organs. It plays a special role in renal and gonadal development, organs in which WT1 deleterious variants determine well-e...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Endocrine and Metabolic Science |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666396123000201 |