Macrophage Polarization and Alveolar Bone Healing Outcome: Despite a Significant M2 Polarizing Effect, VIP and PACAP Treatments Present a Minor Impact in Alveolar Bone Healing in Homeostatic Conditions

Macrophage Polarization and Alveolar Bone Healing Outcome: Despite a Significant M2 Polarizing Effect, VIP and PACAP Treatments Present a Minor Impact in Alveolar Bone Healing in Homeostatic Conditions

Host inflammatory immune response comprises an essential element of the bone healing process, where M2 polarization allegedly contributes to a favorable healing outcome. In this context, immunoregulatory molecules that modulate host response, including macrophage polarization, are considered potenti...

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Bibliographic Details
Main Authors: Michelle de Campos Soriani Azevedo, Angélica Cristina Fonseca, Priscila Maria Colavite, Jéssica Lima Melchiades, André Petenuci Tabanez, Ana Campos Codo, Alexandra Ivo de Medeiros, Ana Paula Favaro Trombone, Gustavo Pompermaier Garlet
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
VIP
PACAP
bone healing
M2 macrophages
osteoimmunology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.782566/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.782566/full

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