DNA-Methylation-Caused Downregulation of <i>miR-30</i> Contributes to the High Expression of XPO1 and the Aggressive Growth of Tumors in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma is one of the most aggressive cancers, with high mortality in the United States. One of the important signal transduction proteins involved in the regulation of pancreatic cancer&#8217;s aggressive progression is the nuclear export protein (XPO1). High expression...

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Bibliographic Details
Main Authors: Asfar S. Azmi, Yiwei Li, Amro Aboukameel, Irfana Muqbil, Philip A. Philip, Ramzi M. Mohammad
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/8/1101