Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis

Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis

Protracted bacterial bronchitis (PBB) in young children is characterised by prolonged wet cough, prominent airway interleukin (IL)-1β expression and infection, often with nontypeable Haemophilus influenzae (NTHi). The mechanisms responsible for IL-1-driven inflammation in PBB are poorly understood....

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Bibliographic Details
Main Authors: Alice C-H. Chen, Hai B. Tran, Yang Xi, Stephanie T. Yerkovich, Katherine J. Baines, Susan J. Pizzutto, Melanie Carroll, Avril A.B. Robertson, Matthew A. Cooper, Kate Schroder, Jodie L. Simpson, Peter G. Gibson, Greg Hodge, Ian B. Masters, Helen M. Buntain, Helen L. Petsky, Samantha J. Prime, Anne B. Chang, Sandra Hodge, John W. Upham
Format: Article
Language:English
Published: European Respiratory Society 2018-03-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/4/1/00130-2017.full

Internet

http://openres.ersjournals.com/content/4/1/00130-2017.full

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