Overexpression of LPCAT1 enhances endometrial cancer stemness and metastasis by changing lipid components and activating TGF-β/Smad2/3 signaling pathway

Overexpression of LPCAT1 enhances endometrial cancer stemness and metastasis by changing lipid components and activating TGF-β/Smad2/3 signaling pathway

The incidence of endometrial cancer (EC) increases annually and tends to occur in younger women. A particularly important relationship exists between EC and metabolic disorders. As one of the most important components of lipid metabolism, phospholipids play an indispensable role in metabolic balance...

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Bibliographic Details
Main Authors: Zhao Tianyi, Sun Rui, Ma Xiaohong, Wei Lina, Hou Yixin, Song Kun, Jiang Jie
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-07-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
endometrial cancer
lipid
LPCAT1
stemness
TGF-β/Smad2/3 signaling pathway
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022076

Internet

https://www.sciengine.com/doi/10.3724/abbs.2022076

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