BACE cleavage of APP does not drive the diabetic phenotype of PLB4 mice

Background: Alzheimer's Disease (AD) and Type 2 Diabetes Mellitus (T2DM), two prevalent diseases related to ageing, often share common pathologies including increased inflammation, endoplasmic reticulum (ER) stress, and impaired metabolic homeostasis predominantly affecting different organs. Th...

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Bibliographic Details
Main Authors: Z.J. Franklin, L. Croce, R. Dekeryte, M. Delibegovic, B. Platt
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123001560