Understanding microglial responses in large animal models of traumatic brain injury: an underutilized resource for preclinical and translational research

Abstract Traumatic brain injury (TBI) often results in prolonged or permanent brain dysfunction with over 2.8 million affected annually in the U.S., including over 56,000 deaths, with over 5 million total survivors exhibiting chronic deficits. Mild TBI (also known as concussion) accounts for over 75...

Full description

Bibliographic Details
Main Authors: Michael R. Grovola, Catherine von Reyn, David J. Loane, D. Kacy Cullen
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-023-02730-z