The effect of cannabinoid type Ⅱ receptor on the excitability of substantia nigra dopaminergic neurons

The biological effects of cannabinoids are mainly mediated by two members of the G-protein-coupled-receptor family: cannabinoid type 1 receptor (CB1R) and cannabinoid type 2 receptor (CB2R). Unlike CB1R, CB2R is considered a “peripheral” cannabinoid receptor. However, recent studies have found that...

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Bibliographic Details
Main Authors: Sha Zhao, Shunfeng Liu, Yongxin Gong, Zegang Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1522210/full