Virtual Screening of Benzimidazole Derivatives as Potential Triose Phosphate Isomerase Inhibitors with Biological Activity against <i>Leishmania mexicana</i>

Virtual Screening of Benzimidazole Derivatives as Potential Triose Phosphate Isomerase Inhibitors with Biological Activity against <i>Leishmania mexicana</i>

<i>Leishmania mexicana</i> (<i>L. mexicana</i>) is a causal agent of cutaneous leishmaniasis (CL), a “<i>Neglected disease</i>”, for which the search for new drugs is a priority. Benzimidazole is a scaffold used to develop antiparasitic drugs; therefore, it is int...

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Bibliographic Details
Main Authors: Lenci K. Vázquez-Jiménez, Alfredo Juárez-Saldivar, Manuel J. Chan-Bacab, Timoteo Delgado-Maldonado, Luis D. González-Morales, Isidro Palos, Eyra Ortiz-Pérez, Edgar E. Lara-Ramírez, Esther Ramírez-Moreno, Gildardo Rivera
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceuticals
Subjects:
virtual screening
molecular docking
benzimidazole
triosephosphate isomerase
<i>Leishmania mexicana</i>
Online Access:https://www.mdpi.com/1424-8247/16/3/390

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https://www.mdpi.com/1424-8247/16/3/390

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