Experimental Aristolochic Acid Nephropathy: A Relevant Model to Study AKI-to-CKD Transition

Experimental Aristolochic Acid Nephropathy: A Relevant Model to Study AKI-to-CKD Transition

Aristolochic acid nephropathy (AAN) is a progressive tubulointerstitial nephritis caused by the intake of aristolochic acids (AA) contained in Chinese herbal remedies or contaminated food. AAN is characterized by tubular atrophy and interstitial fibrosis, characterizing advanced kidney disease. It i...

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Bibliographic Details
Main Authors: Thomas Baudoux, Inès Jadot, Anne-Emilie Declèves, Marie-Hélène Antoine, Jean-Marie Colet, Olivia Botton, Eric De Prez, Agnieszka Pozdzik, Cécile Husson, Nathalie Caron, Joëlle L. Nortier
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Medicine
Subjects:
aristolochic acid nephropathy
AKI-to-CKD transition
animal models
renal fibrosis
nephrotoxicants
aristolochic acids
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.822870/full

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https://www.frontiersin.org/articles/10.3389/fmed.2022.822870/full

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