Brain Uptake of Folate Forms in the Presence of Folate Receptor Alpha Antibodies in Young Rats: Folate and Antibody Distribution

In a rat model, following exposure to rat folate receptor alpha antibodies (FRαAb) during gestation, FRαAb accumulates in the placenta and the fetus and blocks folate transport to the fetal brain and produces behavioral deficits in the offspring. These deficits could be prevented with folinic acid....

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Bibliographic Details
Main Authors: Natasha Bobrowski-Khoury, Jeffrey M. Sequeira, Edward V. Quadros
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/15/5/1167