Evening Primrose Extract Modulates TYMS Expression via SP1 Transcription Factor in Malignant Pleural Mesothelioma

Evening Primrose Extract Modulates TYMS Expression via SP1 Transcription Factor in Malignant Pleural Mesothelioma

Purpose: To determine the mechanism of EPE in downregulating TYMS in MPM cancer. Methods: The TYMS mRNA expression with epithelial-to-mesenchymal transition biomarkers and nuclear factor SP1 was assessed using the GEO database in a data set of MPM patients (GSE51024). Invasive MPM cell lines were in...

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Bibliographic Details
Main Authors: Małgorzata Chmielewska-Kassassir, Katarzyna Sobierajska, Wojciech M. Ciszewski, Jakub Kryczka, Andrzej Zieleniak, Lucyna A. Wozniak
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
malignant pleural mesothelioma
evening primrose extract
thymidylate synthase
specificity protein 1 nuclear factor
epithelial-to-mesenchymal transition
Online Access:https://www.mdpi.com/2072-6694/15/20/5003

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https://www.mdpi.com/2072-6694/15/20/5003

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