Glutamatergic dysfunction in Schizophrenia
Abstract The NMDA-R hypofunction model of schizophrenia started with the clinical observation of the precipitation of psychotic symptoms in patients with schizophrenia exposed to PCP or ketamine. Healthy volunteers exposed to acute low doses of ketamine experienced mild psychosis but also negative a...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-12-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-022-02253-w |