In Vitro Metabolism and In Vivo Pharmacokinetics Profiles of Hydroxy-α-Sanshool

In Vitro Metabolism and In Vivo Pharmacokinetics Profiles of Hydroxy-α-Sanshool

Hydroxy-α-sanshool (HAS) is the predominant active compound in <i>Zanthoxylum bungeanum</i> Maxim (ZBM). Our present work was aimed to explore the in vitro metabolism characteristics, and in vivo pharmacokinetic (PK) profile of HAS. Plasma (human), liver microsomes, and hepatocytes (huma...

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Bibliographic Details
Main Authors: Jie Meng, Die Qian, Ruo-Lan Li, Wei Peng, Li Ai
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Toxics
Subjects:
hydroxy-α-sanshool
liver microsomes
metabolism
pharmacokinetics profile
Online Access:https://www.mdpi.com/2305-6304/12/2/100

Internet

https://www.mdpi.com/2305-6304/12/2/100

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