Prevention and intervention studies with telmisartan, ramipril and their combination in different rat stroke models.

<h4>Objectives</h4>The effects of AT1 receptor blocker, telmisartan, and the ACE inhibitor, ramipril, were tested head-to head and in combination on stroke prevention in hypertensive rats and on potential neuroprotection in acute cerebral ischemia in normotensive rats.<h4>Methods&l...

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Bibliographic Details
Main Authors: Christa Thoene-Reineke, Kay Rumschüssel, Kristin Schmerbach, Maxim Krikov, Christina Wengenmayer, Michael Godes, Susanne Mueller, Arno Villringer, Ulrike Steckelings, Pawel Namsolleck, Thomas Unger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21901125/?tool=EBI