Cytotoxic and Antiproliferative Effects of Preussin, a Hydroxypyrrolidine Derivative from the Marine Sponge-Associated Fungus <i>Aspergillus candidus</i> KUFA 0062, in a Panel of Breast Cancer Cell Lines and Using 2D and 3D Cultures

Cytotoxic and Antiproliferative Effects of Preussin, a Hydroxypyrrolidine Derivative from the Marine Sponge-Associated Fungus <i>Aspergillus candidus</i> KUFA 0062, in a Panel of Breast Cancer Cell Lines and Using 2D and 3D Cultures

Preussin, a hydroxyl pyrrolidine derivative isolated from the marine sponge-associated fungus <i>Aspergillus candidus</i> KUFA 0062, displayed anticancer effects in some cancer cell lines, including MCF7. Preussin was investigated for its cytotoxic and antiproliferative effects in breast...

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Bibliographic Details
Main Authors: Fernanda Malhão, Alice A. Ramos, Suradet Buttachon, Tida Dethoup, Anake Kijjoa, Eduardo Rocha
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Marine Drugs
Subjects:
3D cell culture
antiproliferative activity
breast cancer
cytotoxic activity
preussin
Online Access:https://www.mdpi.com/1660-3397/17/8/448

Internet

https://www.mdpi.com/1660-3397/17/8/448

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