Association Between the P2RY12 Receptor Gene Polymorphism and Aspirin Resistance in Patients with Coronary Artery Disease

Introduction. Platelet activation and aggregation are key elements in the development of coronary atherosclerosis. Recent studies have shown that the two polymorphisms of platelet ADP receptor P2RY12 (haplotypes H2 and 34T) are associated with increased platelet aggregation and atherothrombotic risk...

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Bibliographic Details
Main Authors: Ludmila Karazhanova, Sholpan Zhukusheva, Ainur Akilzhanova
Format: Article
Language:English
Published: University Library System, University of Pittsburgh 2014-12-01
Series:Central Asian Journal of Global Health
Subjects:
Online Access:http://cajgh.pitt.edu/ojs/index.php/cajgh/article/view/160