Synthesis, Anticancer and Antibacterial Activity of Salinomycin N-Benzyl Amides

Synthesis, Anticancer and Antibacterial Activity of Salinomycin N-Benzyl Amides

A series of 12 novel monosubstituted N-benzyl amides of salinomycin (SAL) was synthesized for the first time and characterized by NMR and FT-IR spectroscopic methods. Molecular structures of three salinomycin derivatives in the solid state were determined using single crystal X-ray method. All compo...

Full description

Bibliographic Details
Main Authors: Michał Antoszczak, Ewa Maj, Agnieszka Napiórkowska, Joanna Stefańska, Ewa Augustynowicz-Kopeć, Joanna Wietrzyk, Jan Janczak, Bogumil Brzezinski, Adam Huczyński
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Molecules
Subjects:
anticancer activity
antibacterial activity
antitubercular activity
SAR studies
ionophores
Online Access:http://www.mdpi.com/1420-3049/19/12/19435

Internet

http://www.mdpi.com/1420-3049/19/12/19435

Similar Items