Novel circular RNAs of the apoptosis‐related BAX and BCL2L12 genes identified in a chronic lymphocytic leukemia cell line using nanopore sequencing

Novel circular RNAs of the apoptosis‐related BAX and BCL2L12 genes identified in a chronic lymphocytic leukemia cell line using nanopore sequencing

Circular RNAs (circRNAs), a novel RNA type generated by back‐splicing, are key regulators of gene expression, with deregulated expression and established involvement in leukemia. The products of BCL2 and its homologs, including BAX and BCL2L12, are implicated in chronic lymphocytic leukemia (CLL). H...

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Bibliographic Details
Main Authors: Christos K. Kontos, Paraskevi Karousi, Pinelopi I. Artemaki, Ahmed Abdelgawad, Aspasia Dimitriadou, Nikolaos P. Machairas, Diamantis C. Sideris, Vasiliki Pappa, Andreas Scorilas, Mona Batish, Sotirios G. Papageorgiou
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:FEBS Open Bio
Subjects:
BCL2 family
circRNA
pro‐apoptotic
single‐molecule fluorescence in situ hybridization
third generation (long‐read) sequencing
transcriptomics
Online Access:https://doi.org/10.1002/2211-5463.13672

Internet

https://doi.org/10.1002/2211-5463.13672

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