Synthesis and In Vitro Antiproliferative Activity of New 1-Phenyl-3-(4-(pyridin-3-yl)phenyl)urea Scaffold-Based Compounds

Synthesis and In Vitro Antiproliferative Activity of New 1-Phenyl-3-(4-(pyridin-3-yl)phenyl)urea Scaffold-Based Compounds

A new series of 1-phenyl-3-(4-(pyridin-3-yl)phenyl)urea derivatives were synthesized and subjected to in vitro antiproliferative screening against National Cancer Institute (NCI)-60 human cancer cell lines of nine different cancer types. Fourteen compounds 5a–n were synthesized with three different...

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Bibliographic Details
Main Authors: Mohammad M. Al-Sanea, Mohammed Safwan Ali Khan, Ahmed Z. Abdelazem, So Ha Lee, Pooi Ling Mok, Mohammed Gamal, Mohamed E. Shaker, Muhammad Afzal, Bahaa G. M. Youssif, Nesreen Nabil Omar
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Molecules
Subjects:
cancer
cell line
synthesis
urea derivatives
antiproliferative
activity
Online Access:http://www.mdpi.com/1420-3049/23/2/297

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http://www.mdpi.com/1420-3049/23/2/297

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