Inhibition of the Activating Transcription Factor 6 Branch of Endoplasmic Reticulum Stress Ameliorates Brain Injury after Deep Hypothermic Circulatory Arrest

Inhibition of the Activating Transcription Factor 6 Branch of Endoplasmic Reticulum Stress Ameliorates Brain Injury after Deep Hypothermic Circulatory Arrest

Neurological dysfunction is a common complication of deep hypothermic circulatory arrest (DHCA). Endoplasmic reticulum (ER) stress plays a role in neuronal ischemia-reperfusion injury; however, it is unknown whether it contributes to DHCA-induced brain injury. Here, we aimed to investigate the role...

Full description

Bibliographic Details
Main Authors: You-Peng Zhang, Qin Yang, Yi-Ai Li, Ming-Huan Yu, Guo-Wei He, Yu-Xiang Zhu, Zhi-Gang Liu, Xiao-Cheng Liu
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Journal of Clinical Medicine
Subjects:
apoptosis
ATF6
brain injury
deep hypothermic circulatory arrest
endoplasmic reticulum stress
Online Access:https://www.mdpi.com/2077-0383/12/3/814

Internet

https://www.mdpi.com/2077-0383/12/3/814

Similar Items