The Role of PKM2 in Metabolic Reprogramming: Insights into the Regulatory Roles of Non-Coding RNAs

The Role of PKM2 in Metabolic Reprogramming: Insights into the Regulatory Roles of Non-Coding RNAs

Pyruvate kinase is a key regulator in glycolysis through the conversion of phosphoenolpyruvate (PEP) into pyruvate. Pyruvate kinase exists in various isoforms that can exhibit diverse biological functions and outcomes. The pyruvate kinase isoenzyme type M2 (PKM2) controls cell progression and surviv...

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Bibliographic Details
Main Authors: Dexter L. Puckett, Mohammed Alquraishi, Winyoo Chowanadisai, Ahmed Bettaieb
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
pyruvate kinases
cancer metabolism
metabolic reprogramming
long non-coding RNAs
Online Access:https://www.mdpi.com/1422-0067/22/3/1171

Internet

https://www.mdpi.com/1422-0067/22/3/1171

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