Genetic glucocorticoid receptor variants differ between ethnic groups but do not explain variation in age of diabetes onset, metabolic and inflammation parameters in patients with type 2 diabetes

Genetic glucocorticoid receptor variants differ between ethnic groups but do not explain variation in age of diabetes onset, metabolic and inflammation parameters in patients with type 2 diabetes

AimsThe effect of excess glucocorticoid receptor (GR) stimulation through glucocorticoid medication or cortisol on glucose metabolism is well established. There are genetic GR variants that result in increased or decreased GR stimulation. We aimed to determine the prevalence of genetic GR variants i...

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Bibliographic Details
Main Authors: Mohamed Ahdi, Maaike C. Gerards, Paul H.M. Smits, Eelco W. Meesters, Dees P. M. Brandjes, Max Nieuwdorp, Victor E. A. Gerdes
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Endocrinology
Subjects:
glucocorticoid receptor
diabetes
glucocorticoid medication
cortisol
glucose metabolism
ethnicity
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1200183/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1200183/full

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