Differential expression of HIF-1α in CD44<sup>+</sup>CD24<sup>-/low </sup>breast ductal carcinomas

Differential expression of HIF-1α in CD44<sup>+</sup>CD24<sup>-/low </sup>breast ductal carcinomas

<p>Abstract</p> <p>Background</p> <p>Cancer stem cell (CSC) hypothesis postulates that tumors are maintained by a self-renewing CSC population that is also capable of differentiating into non-self-renewing cell populations that constitute the bulk of tumor. Stem cells r...

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Bibliographic Details
Main Authors: Soares Fernando A, Zorgetto Verônica A, Oliveira Lucinei R, Soave Danilo F, Silveira Giórgia G, Zanetti Juliana S, Oliveira-Costa João, Zucoloto Sérgio, Ribeiro-Silva Alfredo
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Diagnostic Pathology
Subjects:
breast cancer
CD44
CD24
HIF-1α
hypoxia
immunohistochemistry
prognosis
stem cell
Online Access:http://www.diagnosticpathology.org/content/6/1/73

Internet

http://www.diagnosticpathology.org/content/6/1/73

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