Endothelial Nitric Oxide Synthase G894T Polymorphism Associates with Disease Severity in Puumala Hantavirus Infection.

Hantavirus infections are characterized by both activation and dysfunction of the endothelial cells. The underlying mechanisms of the disease pathogenesis are not fully understood. Here we tested the hypothesis whether the polymorphisms of endothelial nitric oxide synthase, eNOS G894T, and inducible...

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Bibliographic Details
Main Authors: Sirpa Koskela, Outi Laine, Satu Mäkelä, Tanja Pessi, Sari Tuomisto, Heini Huhtala, Pekka J Karhunen, Ilkka Pörsti, Jukka Mustonen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4641644?pdf=render