Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells

Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells

Summary: While dysbiosis in the gut is implicated in the impaired induction of oral tolerance generated in mesenteric lymph nodes (MesLNs), how dysbiosis affects this process remains unclear. Here, we describe that antibiotic-driven gut dysbiosis causes the dysfunction of CD11c+CD103+ conventional d...

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Bibliographic Details
Main Authors: Tomohiro Fukaya, Tomofumi Uto, Shuya Mitoma, Hideaki Takagi, Yotaro Nishikawa, Moe Tominaga, Narantsog Choijookhuu, Yoshitaka Hishikawa, Katsuaki Sato
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723004424

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http://www.sciencedirect.com/science/article/pii/S2211124723004424

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